Eric van den Eycken

Erik Van der Eycken is Professor Organic Chemistry and head of the Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC) at the University of Leuven (KU Leuven), Belgium. He received his Master diploma (1982) and his PhD degree (1987) in organic chemistry from the University of Ghent, Belgium, with Prof. M. Vandewalle on the total synthesis and structural elucidation of Specionin, an iridoid insect antifeedant. From 1988 to 1992 he worked as a scientific researcher at the R&D-laboratories of AGFA-Gevaert, Mortsel, Belgium. He moved back to the University of Ghent as a scientific collaborator on photo-induced reactions with Prof. D. De Keukeleire and Prof. P. Herdewijn on HIV-active drugs (1992-1995). From 1995-1997 he was connected to the Flemish Inter-University Institute for Biotechnology (VIB), Ghent, with Prof. M. Van Montagu where he was involved in the synthesis of intermediates for the elucidation of biological reaction pathways. In 1997 he became Doctor-Assistent at the KU Leuven, Belgium in the group of Prof. G. Hoornaert, where he was involved in heterocyclic chemistry. He spent time as visiting scientist at the University of Graz (2002) with Prof. C. O. Kappe on microwave-assisted hetero-Diels-Alder reactions, at The Scripps Research Institute (La Jolla, USA) (2003) in the group of K. B. Sharpless, on microwave-assisted click chemistry, and at Uppsala University (2004) with Prof. M. Larhed and Prof. A. Hallberg on microwave-assisted carbonylations. He was appointed part-time professor in 2003 at KU Leuven and started his independent academic career. In 2007 he became full-time professor at the same university. He is presently Visiting Professor at Peoples’ Friendship University of Russia, Moscow (RUDN University). The main focus of his research is the investigation of the application of microwave irradiation in different domains of organic synthesis, i.e. synthesis of bioactive natural product analogues and heterocyclic molecules applying transition metal-catalyzed reactions (i.a. homogeneous and heterogeneous (nanoparticles) gold catalysis), C-H activation, multicomponent reactions (MCRs), post-MCR modifications, and solid phase organic synthesis. Also Flow Chemistry has been recently addressed. He is presently author of >260 scientific manuscripts in peer reviewed journals and books and has an H-index of 41.


Five most important publications (see a complete list)

  • F. Lima, U. K. Sharma, L. Grunenberg, D. Saha, S. Johannsen, J. Sedelmeier, E. V. Van der Eycken,* S.V. Ley.* (2017). A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters. Angew. Chem. Int. Ed., 56, 15136–15140, 2017 (IF most recent: 12.102).
  • Schröder, F., Sharma, U. K., Mertens, M., Devred, F., Debecker, D., Luque, R., Van der Eycken, E. V. (2016). Silver-Nanoparticle-Catalyzed Dearomatization of Indoles toward 3-Spiroindolenines via a 5-exo-dig Spirocyclization. ACS Catalysis, 6(12), 8156-8161 (IF most recent: 11.384).
  • Modha, S. G., Kumar, A., Vachhani, D. D., Jacobs, J., Sharma, S. K., Parmar, V. S., Van Meervelt, L., Van der Eycken, E. V. (2012). Diversity-Oriented Approach to Spiroindolines: Post-Ugi Gold- Catalyzed Diastereoselective Domino Cyclization, Angewandte Chemie - International Edition, 51, 9572-9575 (citations: 86) (IF2012: 13.46) (IF most recent: 12.102).
  • Kappe, C. , Van der Eycken, E. (2010). Click chemistry under non-classical reaction conditions.
  • Chemical Society Reviews, 39 (4) , 1280-1290 (citations: 278) (IF2010: 26.59) (IF most recent: 40.18).
  • Appukkuttan, P., Dehaen, W., Fokin, V., Van der Eycken, E. (2004). A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles via a copper(I)-catalyzed three-component reaction. Organic Letters, 6 (23), 4223-4225 (citations: 469) (IF2004: 4.09) (IF most recent: 6.49).